HRID1591533

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6571

1-Chloropropan-2-one

C3H5ClO

HCID12980

2-Butynedioic acid, dimethyl ester

C6H6O4

HCID28015

Sodium hydrosulfide

HNaS

PRODUCTS

生成物

HCID10608080

2-Thiophenecarboxylic acid, 5-acetyl-4-hydroxy-, methyl ester

C8H8O4S

PROCEDURE

实验过程

According to the description in Synth. Commun., 1996, 26, 1083, methyl 2-acetyl-3-hydroxythiophene-5-carboxylate was synthesized with chloroacetone, dimethyl acetylene dicarboxylate and sodium hydrosulfide as starting materials (yield: 60%).