HRID1591534

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14798

Sodium Hydroxide

HNaO

HCID10608080

2-Thiophenecarboxylic acid, 5-acetyl-4-hydroxy-, methyl ester

C8H8O4S

PRODUCTS

生成物

HCID13352352

1-(3-Hydroxythiophen-2-yl)ethan-1-one

C6H6O2S

收率 58%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID67118996

未命名化合物

PROCEDURE

实验过程

The above-obtained methyl 2-acetyl-3-hydroxythiophene-5-carboxylate was hydrolyzed with an aqueous solution of sodium hydroxide, the hydrolyzate was heated with copper-quinoline to be decarboxylated, thereby the objective 2-acetyl-3-hydroxythiophene was obtained (yield: 58%).