HCID 67132057, compound → HCID 67132009, compound

Participants

Reaction Steps

1.56 g of tert-butyl 1-benzyl-4-piperidinyl[3-(4-cyanophenoxy)propyl]carbamate was dissolved in 20 ml of methanol, and then, 0.30 g of 5% palladium-carbon was added to the solution, followed by stirring under a hydrogen atmosphere at room temperature under an atmospheric pressure for 18 hours. After completion of the reaction, the catalyst was removed, and the solvent was then removed under a reduced pressure to obtain 1.05 g of tert-butyl 3-(4-cyanophenoxy)propyl(4-piperidinyl)carbamate.

Provenance & Evidence