Ethylenediamine → HCID 69422985, compound

HRID 1591750Notes

Reaction equation

[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][C:11]([N:13]([CH2:15][CH2:16][CH2:17][NH:18][CH2:19][S:20]([C:23]2[CH:28]=[CH:27][CH:26]=[C:25]([Cl:29])[C:24]=2[Cl:30])(=[O:22])=[O:21])[CH3:14])=[O:12])=[CH:5][CH:4]=1)#[N:2].[S].[CH2:32](N)[CH2:33][NH2:34]>>[Cl:30][C:24]1[C:25]([Cl:29])=[CH:26][CH:27]=[CH:28][C:23]=1[S:20]([CH2:19][NH:18][CH2:17][CH2:16][CH2:15][N:13]([CH3:14])[C:11](=[O:12])[CH2:10][CH2:9][C:6]1[CH:5]=[CH:4][C:3]([C:1]2[NH:34][CH2:33][CH2:32][N:2]=2)=[CH:8][CH:7]=1)(=[O:22])=[O:21]

Participants

Reactant 3

HCID 3301Ethylenediamine

HCID 5362487Sulfur

HCID 69428903HCID 69428903, compound

Product 1

HCID 69422985HCID 69422985, compound

Procedure

Analogously to 13b), N-{3-[(2,3-dichlorobenzenesulphonyl)methylamino]propyl}-3-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-N-methylpropionamide was prepared from 0.7 g (1.49 mmol) of 3-(4-cyanophenyl)-N-{3-[(2,3-dichlorobenzenesulphonyl)methylamino]propyl}-N-methylpropionamide, 0.1 g (3.12 mmol) of sulphur and 3 ml of ethylenediamine.

Sources & evidence

ORD record: ord-e0307b70a07449b997f382b0d4699cdf
Source dataset: uspto-grants-2007_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07291642B2

Reaction notes

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