Ethylenediamine → HCID 11713326, compound

HRID 1591751Notes

Reaction equation

[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][C:11]([N:13]([CH3:34])[CH2:14][CH2:15][CH2:16][N:17]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[S:18]([C:21]2[CH:26]=[CH:25][C:24]([CH3:27])=[CH:23][CH:22]=2)(=[O:20])=[O:19])=[O:12])=[CH:5][CH:4]=1)#[N:2].[S].[CH2:36](N)[CH2:37][NH2:38]>>[NH:2]1[CH2:36][CH2:37][N:38]=[C:1]1[C:3]1[CH:4]=[CH:5][C:6]([CH2:9][CH2:10][C:11]([N:13]([CH3:34])[CH2:14][CH2:15][CH2:16][N:17]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[S:18]([C:21]2[CH:22]=[CH:23][C:24]([CH3:27])=[CH:25][CH:26]=2)(=[O:19])=[O:20])=[O:12])=[CH:7][CH:8]=1

Participants

Reactant 3

HCID 3301Ethylenediamine

HCID 5362487Sulfur

HCID 69425968HCID 69425968, compound

Product 1

HCID 11713326HCID 11713326, compound

Procedure

Analogously to 13b), 3-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-N-methyl-N-{3-[phenyl(toluene-4-sulphonyl)amino]propyl}propionamide was prepared from 1.82 g (3.83 mmol) of 3-(4-cyanophenyl)-N-methyl-N-{3-[phenyl(toluene-4-sulphonyl)amino]propyl}propionamide, 122 mg (3.83 mmol) of sulphur and 7 ml of ethylenediamine.

Sources & evidence

ORD record: ord-232d9ce51baf4a9489d696136235e43e
Source dataset: uspto-grants-2007_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07291642B2

Reaction notes

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