Ethylenediamine → HCID 69423930, compound

HRID 1591752Notes

Reaction equation

[Cl:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([S:9]([CH2:12][NH:13][CH2:14][CH2:15][NH:16][C:17](=[O:28])[CH2:18][CH2:19][C:20]2[CH:25]=[CH:24][C:23]([C:26]#[N:27])=[CH:22][CH:21]=2)(=[O:11])=[O:10])=[C:4]([CH3:29])[CH:3]=1.[S].[CH2:31](N)[CH2:32][NH2:33]>>[Cl:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5]([S:9]([CH2:12][NH:13][CH2:14][CH2:15][NH:16][C:17](=[O:28])[CH2:18][CH2:19][C:20]2[CH:25]=[CH:24][C:23]([C:26]3[NH:33][CH2:32][CH2:31][N:27]=3)=[CH:22][CH:21]=2)(=[O:10])=[O:11])=[C:4]([CH3:29])[CH:3]=1

Participants

Reactant 3

HCID 3301Ethylenediamine

HCID 5362487Sulfur

HCID 69421839HCID 69421839, compound

Product 1

HCID 69423930HCID 69423930, compound

Procedure

Analogously to 13b), N-{2-[(4-chloro-2,5-dimethylbenzenesulphonyl)methylamino]ethyl}-3-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]propionamide was prepared from 1.15 g (2.65 mmol) of N-{2-[(4-chloro-2,5-dimethylbenzenesulphonyl)methylamino]ethyl}-3-(4-cyanophenyl)propionamide, 85 mg (2.65 mmol) of sulphur and 4 ml of ethylenediamine.

Sources & evidence

ORD record: ord-f6ce4cb6af374cfcbd72d32b565c8981
Source dataset: uspto-grants-2007_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07291642B2

Reaction notes

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