Ethylenediamine → HCID 131726660, compound

HRID 1591761Notes

Reaction equation

[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][N:11]([CH2:17][S:18]([C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([Cl:27])[C:22]=2[Cl:28])(=[O:20])=[O:19])[CH:12]2[CH2:16][CH2:15][CH2:14][CH2:13]2)=[CH:5][CH:4]=1)#[N:2].CNC=[O:32].[S].[CH2:34]([NH2:37])[CH2:35]N>>[Cl:28][C:22]1[C:23]([Cl:27])=[CH:24][CH:25]=[CH:26][C:21]=1[S:18]([CH2:17][NH:11][CH:12]1[CH2:13][CH2:14][CH2:15][CH2:16]1)(=[O:19])=[O:20].[NH:37]1[CH2:34][CH2:35][N:2]=[C:1]1[C:3]1[CH:4]=[CH:5][C:6]([CH2:9][CH2:10][N:11]([CH3:12])[CH:17]=[O:32])=[CH:7][CH:8]=1

Participants

Reactant 3

HCID 3301Ethylenediamine

HCID 5362487Sulfur

HCID 131726662HCID 131726662, compound

Product 1

HCID 131726660HCID 131726660, compound

Procedure

Analogously to 13b), 3-[(2,3-dichlorobenzenesulphonyl)methylamino]cyclopentane-N-{2-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]ethyl}-N-methylcarboxamide was prepared from 0.185 g (0.374 mmol) of N-[2-(4-cyanophenyl)ethyl]-3-[(2,3-dichlorobenzenesulphonyl)methylamino]cyclopentane-N-methylcarboxamide, 6.0 mg (0.187 mmol) of sulphur and 1 ml of ethylenediamine.

Sources & evidence

ORD record: ord-6b4352df603841d39dc2bb7e028afe69
Source dataset: uspto-grants-2007_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07291642B2

Reaction notes

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