Ethylenediamine → HCID 69421765, compound

HRID 1591763Notes

Reaction equation

[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][N:11]([CH:30]2[CH2:32][CH2:31]2)[C:12](=[O:29])[CH2:13][CH2:14][CH2:15][NH:16][CH2:17][S:18]([C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([Cl:27])[C:22]=2[Cl:28])(=[O:20])=[O:19])=[CH:5][CH:4]=1)#[N:2].[S].[CH2:34](N)[CH2:35][NH2:36]>>[CH:30]1([N:11]([CH2:10][CH2:9][C:6]2[CH:5]=[CH:4][C:3]([C:1]3[NH:36][CH2:35][CH2:34][N:2]=3)=[CH:8][CH:7]=2)[C:12](=[O:29])[CH2:13][CH2:14][CH2:15][NH:16][CH2:17][S:18]([C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([Cl:27])[C:22]=2[Cl:28])(=[O:20])=[O:19])[CH2:31][CH2:32]1

Participants

Reactant 3

HCID 3301Ethylenediamine

HCID 5362487Sulfur

HCID 69425514HCID 69425514, compound

Product 1

HCID 69421765HCID 69421765, compound

Procedure

Analogously to 13b), N-cyclopropyl-4-[(2,3-dichlorobenzenesulphonyl)methylamino]-N-{2-[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]ethyl}butyramide was prepared from 0.84 g (1.70 mmol) of N-[2-(4-cyanophenyl)ethyl]-N-cyclopropyl-4-[(2,3-dichlorobenzenesulphonyl)methylamino]butyramide, 0.143 g (4.46 mmol) of sulphur and 3 ml of ethylenediamine.

Sources & evidence

ORD record: ord-8fa5b0317799405ea02d7ac82148f1df
Source dataset: uspto-grants-2007_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07291642B2

Reaction notes

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