Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1591814Generated: November 2, 2026

4-(Propan-2-yl)benzene-1-sulfonyl chloride → N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]4-isopropylbenzenesulfonamide

https://huagongshe.com/reaction/1591814

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Propan-2-yl)benzene-1-sulfonyl chlorideHCID 2734882—
Reactant5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrileHCID 16050430—
ProductN-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]4-isopropylbenzenesulfonamideHCID 16050905—

Reaction Steps

The title compound was prepared according to general procedure for sulfonylation of 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile using 4-isopropyl-benzenesulfonyl chloride (120 mg, 0.55 mmol) to provide N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]4-isopropylbenzenesulfonamide (0.049 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07291643B2
Source datasetuspto-grants-2007_11
ORD IDord-8884d75b57874ca08ead91c823e2cc3d
Source noteuspto-grants-2007_11