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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1591936Generated: October 30, 2026

Sodium Hydroxide → HCID 131726666, compound

https://huagongshe.com/reaction/1591936

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant2-[2-(3,5-Bis-trifluoromethyl-benzenesulfonylamino)-6,7-dihydro-4H-thiazolo-[5,4-c]pyridin-5-yl]-4-trifluoromethyl-benzamideHCID 9938946—
SolventEthanolHCID 702—
ProductHCID 131726666HCID 131726666—

Reaction Steps

1.9 ml of an aqueous 0.1 M NaOH solution are added to a solution of 118 mg of 2-[2-(3,5-bis-trifluoromethyl-benzenesulfonylamino)-6,7-dihydro-4H-thiazolo-[5,4-c]pyridin-5-yl]-4-trifluoromethyl-benzamide in 10 ml of EtOH, and the mixture obtained is stirred at RT for 5 minutes. From the mixture obtained solvent is evaporated and the evaporation residue obtained is subjected to lyophilisation. [2-(3,5-Bis-trifluoromethyl-benzenesulfonylamino)-6,7-dihydro-4H-thiazolo-[5,4-c]pyridin-5-yl]-4-trifluoromethyl-benzamide sodium salt is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07291734B2
Source datasetuspto-grants-2007_11
ORD IDord-b12f891470e4489982346a243b610541
Source noteuspto-grants-2007_11