Piperazine → 1-[2-(Propan-2-yloxy)phenyl]piperazine

HRID 1592712Notes

Reaction equation

[NH:1]1[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.Br[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[O:14][CH:15]([CH3:17])[CH3:16]>>[CH:15]([O:14][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=1[N:1]1[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1)([CH3:17])[CH3:16]

Participants

Reactant 2

HCID 4837Piperazine

HCID 219254271-Bromo-2-[(propan-2-yl)oxy]benzene

Product 1

HCID 109440161-[2-(Propan-2-yloxy)phenyl]piperazine

Procedure

The title compound was prepared in a manner similar to Preparation 1A except that piperazine was coupled to 1-bromo-2-isopropoxy-benzene. LRMS (ESI+): 221.4 (M+1)

Sources & evidence

ORD record: ord-205d63af5d4048bf8ddf5084894430d0
Source dataset: uspto-grants-2007_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07291619B2

Reaction notes

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