Piperazine → 1-(2-Cyclohexyl-phenyl]piperazine

HRID 1592715Notes

Reaction equation

HRID 1592715 reaction equation
[NH:1]1[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.Br[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[CH:14]1[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>>[CH:14]1([C:9]2[CH:8]=[CH:13][CH:12]=[CH:11][C:10]=2[N:1]2[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]2)[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 109445021-Bromo-2-cyclohexylbenzene

Product 1

HCID 231418401-(2-Cyclohexyl-phenyl]piperazine

Procedure

The title compound was prepared in a manner similar to Preparation 1A except that piperazine was coupled to 1-bromo-2-cyclohexyl-benzene.

Sources & evidence

ORD record
ord-3cdb742e61c4487c9b869839e9f4a628
Source dataset
uspto-grants-2007_11
Patent number
US07291619B2

Reaction notes

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