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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1592885Generated: October 31, 2026

3-(Dimethylamino)-1-(4-fluorophenyl)-2-(pyridin-4-yl)prop-2-en-1-one → HCID 178505589, compound

https://huagongshe.com/reaction/1592885

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Dimethylamino)-1-(4-fluorophenyl)-2-(pyridin-4-yl)prop-2-en-1-oneHCID 54518838—
Reactant3-Dimethylamino-1-(3,4-difluorophenyl)-2-(pyridin-4-yl)-2-propen-1-oneHCID 69413090—
ProductHCID 178505589HCID 17850558990%

Reaction Steps

The reaction was carried out in the same manner as in Example 1-2) except for using 2.54 g (8.81 mmol) of 3-dimethylamino-1-(3,4-difluorophenyl)-2-(pyridin-4-yl)-2-propen-1-one obtained in Example 6-1) in place of 3-dimethylamino-1-(4-fluorophenyl)-2-(pyridin-4-yl)-2-propen-1-one to obtain 2.05 g of the title compound as a white powder. (Yield: 90%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07294625B2
Source datasetuspto-grants-2007_11
ORD IDord-5abb74c0ce5a4d6a80d773e6859727d4
Source noteuspto-grants-2007_11