HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanecarbonyl chloride → HCID 10455910, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanecarbonyl chloride | HCID 77637 | — |
| Reactant | HCID 9976519 | HCID 9976519 | — |
| Product | HCID 10455910 | HCID 10455910 | 37.3% |
Reaction Steps
The reaction was carried out in the same manner as in Example 9 except for using 200 mg (0.54 mmol) of 4-(2-aminopyridin-4-yl)-3-(4-fluorophenyl)-1-([1,2,4]triazolo-[4,3-b]pyridazin-6-yl)-1H-pyrazole obtained by the same reaction as in Example 8-2), and using 59.0 mg (0.56 mmol) of cyclopropylcarbonyl chloride in place of acetic anhydride to obtain 88.6 mg of the title compound as a white powder. (Yield: 37%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07294625B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-763039fd68fc475282a2d487cf537dd7 |
| Source note | uspto-grants-2007_11 |