3-Dimethylamino-1-(4-fluorophenyl)-2-(2-methylthiopyrimidin-4-yl)-2-propen-1-one → HCID 178503425, compound

Participants

Reaction Steps

The reaction was carried out in the same manner as in Example 2-2) except for using 4.13 g (13.0 mmol) of 3-dimethylamino-1-(4-fluorophenyl)-2-(2-methylthiopyrimidin-4-yl)-2-propen-1-one obtained in Example 66-1) in place of 2-(2-t-butoxycarbonylaminopyridin-4-yl)-3-dimethylamino-1-(4-fluorophenyl)-2-propen-1-one to obtain 3.44 g of the title compound as a white powder. (Yield: 93%)

Provenance & Evidence