HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Ethynyl-1-fluoro-4-nitrobenzene → HCID 19702702, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Ethynyl-1-fluoro-4-nitrobenzene | HCID 12687361 | — |
| Catalyst | Pd barium sulfate | HCID 16218511 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 19702702 | HCID 19702702 | — |
Reaction Steps
To a solution of 2-ethynyl-1-fluoro-4-nitro-benzene (70 mg, 0.42 mmol, obtained in Example 71) in 3 mL ethanol, 5% Pd/BaSO4 (48 mg) was added. The mixture was hydrogenated at 1 atm for 1.5 hrs. Catalyst was removed by filtering through a celite pad. The filtrate was concentrated to give pure 1-fluoro-4-nitro-2-vinyl-benzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07294635B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-728e180744624e8f8c559f41448dc995 |
| Source note | uspto-grants-2007_11 |