Sodium methanesulfinate → HCID 58998479, compound

Participants

Reaction Steps

To a slolution of [2-(3-bromo-4-nitro-phenyl)-7-fluoro-1-oxo-1,2-dihydro-isoquinolin-6-yl]-methyl-carbamic acid tert-butyl ester (10 mg, 0.02 mmol) in DMSO 0.5 ml, sodium methanesulfinate (62 mg, 0.06 mmol) was added. The reaction mixture was subjected to microwave irradiation (temperature 12° C.) for 45 seconds. A precipitate was formed and collected by filtration to give [7-fluoro-2-(3-methanesulfonyl-4-nitro-phenyl)-1-oxo-1,2-dihydro-isoquinolin-6-yl]-methyl-carbamic acid tert-butyl ester.

Provenance & Evidence