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HRID1593189

反应详情

EQUATION

反应方程式

HRID 1593189 的结构方程式

REACTANTS

反应物

4
结构：COC(=O)CC(C)=O
HCID7757

Methyl acetoacetate

C5H8O3

结构：N[C@@H]1CCCC[C@H]1O
HCID735777

(1R,2R)-2-Aminocyclohexanol

C6H13NO

结构：NCCC1CC1
HCID10240761

2-Cyclopropylethylamine

C5H11N

结构：O=C(CBr)c1cc(C(F)(F)F)ccc1C(F)(F)F
HCID22137987

1-[2,5-Bis(trifluoromethyl)phenyl]-2-bromoethanone

C10H5BrF6O

PRODUCTS

生成物

1
结构：Cc1c(C(=O)N[C@@H]2CCCC[C@H]2O)cc(-c2cc(C(F)(F)F)ccc2C(F)(F)F)n1CCC1CC1
HCID10255487

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in analogy to Example 68, using 3-oxo-butyric acid methyl ester as compound of formula R, 1-(2,5-bis-trifluoromethyl-phenyl)-2-bromo-ethanone as compound of formula S, 2-cyclopropyl-ethylamine as R3—(CH2)m—NH2 and (1R,2R)-2-amino-cyclohexanol as R1R2NH, MS (ISP) 503.1 (M+H)+.