HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20786539, compound → HCID 20786554, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20786539 | HCID 20786539 | — |
| Catalyst | Nickel | HCID 935 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 20786554 | HCID 20786554 | 104.1% |
Reaction Steps
Methyl [4-(4-methoxy-2-nitrophenyl)aminosulfonyl-3,5-dimethylphenoxy]acetate (Intermediate A2, 8.1 g, 0.019 mol) in 200 mL ethyl acetate was stirred with Raney nickel (0.75 g) for 30 min and filtered through a celite pad with the aid of an additional 100 mL of ethyl acetate. The filtrate was mixed with platinum oxide (0.40 g, 0.0018 mol) and hydrogenated to give 7.8 g (100%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07294716B2 |
| Source dataset | uspto-grants-2007_11 |
| ORD ID | ord-1755d91b0fb24b19af65a3fd23bd7eb5 |
| Source note | uspto-grants-2007_11 |