Tetrahydrofuran → 4,6-Di-t-butyl-5-hydroxy-2-methyl-2,3-dihydrobenzofuran-2-carboxylic acid

HRID 159341Notes

Reaction equation

HRID 159341 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[c:6]([O:22][Si:23]([CH3:24])([CH3:25])[CH3:26])[c:7]([C:18]([CH3:19])([CH3:20])[CH3:21])[cH:8][c:9]2[c:10]1[CH2:11][C:12]([C:14](=[O:15])[OH:16])([CH3:17])[O:13]2.[CH2:28]([N+:29]([CH2:30][CH2:31][CH2:32][CH3:33])([CH2:34][CH2:35][CH2:36][CH3:37])[CH2:38][CH2:39][CH2:40][CH3:41])[CH2:42][CH2:43][CH3:44].[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[F-:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[c:6]([OH:22])[c:7]([C:18]([CH3:19])([CH3:20])[CH3:21])[cH:8][c:9]2[c:10]1[CH2:11][C:12]([C:14](=[O:15])[OH:16])([CH3:17])[O:13]2

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 232880354,6-Di-t-butyl-2-methyl-5-trimethylsilyloxy-2,3-dihydrobenzofuran-2-carboxylic acid

Product 1

HCID 154857264,6-Di-t-butyl-5-hydroxy-2-methyl-2,3-dihydrobenzofuran-2-carboxylic acid

Sources & evidence

ORD record
ord-fa9125652d074f87a447bb17c96ea01a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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