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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1593426Generated: November 1, 2026

5-(5-Bromo-2-pyridin-4-ylfuran-3-yl)indan-1-one → 5-{5-[2-(2-Morpholin-4-ylethoxy)pyrimidin-5-yl]-2-pyridin-4ylfuran-3-yl}indan-1-one

https://huagongshe.com/reaction/1593426

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(5-Bromo-2-pyridin-4-ylfuran-3-yl)indan-1-oneHCID 69428384—
Reactant4-[2-(5-Trimethylstannanylpyrimidin-2-yloxy)ethyl]morpholineHCID 69433501—
Product5-{5-[2-(2-Morpholin-4-ylethoxy)pyrimidin-5-yl]-2-pyridin-4ylfuran-3-yl}indan-1-oneHCID 6943349748%

Reaction Steps

The title compound (0.11 g, 48%) was prepared from the product of Step 2 and the product from Example 5 Step 9 using the method of Example 5 Step 10; MS(ES+) m/e 483 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07297694B2
Source datasetuspto-grants-2007_11
ORD IDord-741cd7448daa4981a6b911fda13dcc8f
Source noteuspto-grants-2007_11