Piperazine → HCID 69429958, compound

HRID 1593431Notes

Reaction equation

CS([C:5]1[N:10]=[CH:9][C:8]([C:11]2[O:15][C:14]([C:16]3[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=3)=[C:13]([C:22]3[CH:23]=[C:24]4[C:28](=[CH:29][CH:30]=3)[C:27](=[O:31])[CH2:26][CH2:25]4)[CH:12]=2)=[CH:7][N:6]=1)(=O)=O.[NH:32]1[CH2:37][CH2:36][NH:35][CH2:34][CH2:33]1>>[N:32]1([C:5]2[N:10]=[CH:9][C:8]([C:11]3[O:15][C:14]([C:16]4[CH:21]=[CH:20][N:19]=[CH:18][CH:17]=4)=[C:13]([C:22]4[CH:23]=[C:24]5[C:28](=[CH:29][CH:30]=4)[C:27](=[O:31])[CH2:26][CH2:25]5)[CH:12]=3)=[CH:7][N:6]=2)[CH2:37][CH2:36][NH:35][CH2:34][CH2:33]1

Participants

Reactant 2

HCID 4837Piperazine

HCID 69430943HCID 69430943, compound

Product 1

HCID 69429958HCID 69429958, compoundYield 65%

Procedure

The title compound (0.10 g, 65%) was prepared from the product of Example 7 Step 6 and piperazine using the method of Example 7 Step 7; MS(ES+) m/e 438 [M+H]+.

Sources & evidence

ORD record: ord-84aa1404cf13430297edcf43f7df1c4e
Source dataset: uspto-grants-2007_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07297694B2

Reaction notes

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