Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 136343490 | HCID 136343490 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 136343466 | HCID 136343466 | — |
Reaction Steps
A solution of 2-(1H-Imidazole-2-yl)-thiazole-4-carboxylic acid ethyl ester (190 mg) in 5 mL of MeOH is saturated with NH3 gas, and heated at 60° C. in a sealed tube overnight. After cooled, the reaction mixture is transferred to a round bottle flask and evaporated in vacuo to a solid. LRMS calcd 194, found 195 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07300945B2 |
|---|
| Source dataset | uspto-grants-2007_11 |
|---|
| ORD ID | ord-a8697457e2ca475a9be6a38e48f61c92 |
|---|
| Source note | uspto-grants-2007_11 |
|---|
