m-Chloroperbenzoic acid → HCID 69025582, compound

Participants

Reaction Steps

370 mg of 3-methylthio-5-cyclohexyl-1,2,4-thiadiazole was dissolved in 8 ml of chloroform, 1.12 g of 3-chloroperoxybenzoic acid (content>65%) was added thereto, and the reaction mixture was stirred for 7 hours under ice-cooling. Then, the reaction mixture was added to saturated sodium hydrogensulfite aqueous solution, and separated. The organic layer was washed with sodium hydrogencarbonate aqueous solution, dried over anhydrous sodium sulfate, concentrated to give 444 mg of 3-methylsulfonyl-5-cyclohexyl-1,2,4-thiadiazole.

Provenance & Evidence