m-Chloroperbenzoic acid → HCID 69025990, compound

Participants

Reaction Steps

710 mg of 3-methylthio-5-cyclopentyl-1,2,4-thiadiazole was dissolved in 15 ml of chloroform, 1.89 g of 3-chloroperoxybenzoic acid (content>65%) was added thereto, and the reaction mixture was stirred for 30 minutes under ice-cooling and for 3.5 hours at room temperature. Then, the reaction mixture was added to saturated sodium hydrogensulfite aqueous solution, and separated. The organic layer was washed with sodium hydrogencarbonate aqueous solution, dried over anhydrous sodium sulfate, concentrated to give 804 mg of 3-methylsulfonyl-5-cyclopentyl-1,2,4-thiadiazole.

Provenance & Evidence