Dimethylformamide → (3SR,4RS)-3-(3,4-Dichloro-phenyl)-4-[(3-fluoro-4-trifluoromethyl-benzyl)-methyl-amino]-pyrrolidine-1-carboxylic acid 3-cyano-propyl ester
Reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([c:27]2[cH:28][c:29]([Cl:34])[c:30]([Cl:33])[cH:31][cH:32]2)[CH:11]([N:13]([CH3:14])[CH2:15][c:16]2[cH:17][c:18]([F:26])[c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]2)[CH2:12]1.[K:35][C:36]#[N:37].[O:38]=[CH:39][N:40]([CH3:41])[CH3:42]>>[CH2:2]([CH2:3][CH2:4][O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([c:27]2[cH:28][c:29]([Cl:34])[c:30]([Cl:33])[cH:31][cH:32]2)[CH:11]([N:13]([CH3:14])[CH2:15][c:16]2[cH:17][c:18]([F:26])[c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]2)[CH2:12]1)[C:36]#[N:37]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-8328b7e11b354b29a16533f64ad38f52
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…