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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1594483Generated: October 30, 2026

1-methyl-1H-imidazole-5-carbaldehyde → HCID 58691383, compound

https://huagongshe.com/reaction/1594483

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-methyl-1H-imidazole-5-carbaldehydeHCID 573592—
ReactantN-(4-(6-(2-Amino-4-(trifluoromethyl)phenyl)pyrimidin-4-yloxy)benzo[d]thiazol-2-yl)acetamideHCID 21865046—
ProductHCID 58691383HCID 58691383—

Reaction Steps

N-(4-(6-(2-Amino-4-(trifluoromethyl)phenyl)pyrimidin-4-yloxy)benzo[d]thiazol-2-yl)acetamide (prepared as described in WO04014871) was reacted with 1-methyl-1H-imidazole-5-carbaldehyde (Acros) under the conditions of Example 54 to give the title compound. MS (ESI, pos. ion) m/z: 540 (M+1). Mp: 263.0-265.2° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07301022B2
Source datasetuspto-grants-2007_11
ORD IDord-bb2d392a043c46d385dac18005e3116c
Source noteuspto-grants-2007_11