HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbonic acid, ethyl 2-mercaptoethyl ester → HCID 15549934, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbonic acid, ethyl 2-mercaptoethyl ester | HCID 79728 | — |
| Reactant | 4-(4-Fluoro-benzyl)-piperidine | HCID 3699841 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 15549934 | HCID 15549934 | — |
Reaction Steps
A mixture of 4-(4-fluorobenzyl)piperidine (5.9 g, 30.5 mmol) and ethyl 2-mercaptoethyl carbonate (4.8 g, 32 mmol) was heated to reflux in toluene (250 mL) for 18 hr under a nitrogen atmosphere. The toluene was removed in vacuo and the resulting oil was used without purification in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06284774B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-ff6ecf6aea2f419191c39345aaa90516 |
| Source note | uspto-grants-2001_09 |