4-Methylbenzyl chloride → HCID 23665764, compound

HRID 1594656Notes

Reaction equation

HRID 1594656 reaction equation
[S:1]([O-:4])([O-:3])=[O:2].[Na+:5].[Na+].[CH3:7][C:8]1[CH:15]=[CH:14][C:11]([CH2:12]Cl)=[CH:10][CH:9]=1>O>[Na+:5].[CH3:7][C:8]1[CH:15]=[CH:14][C:11]([CH2:12][S:1]([O-:4])(=[O:3])=[O:2])=[CH:10][CH:9]=1

Participants

4

Reactant 2

HCID 77224-Methylbenzyl chlorideHCID 24437Sodium Sulfite

Product 1

HCID 23665764HCID 23665764, compoundYield 53.1%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a solution of sodium sulfite (14.3 g 113 mmol) in water (60 mL) was added 4-methylbenzyl chloride (15.0 mL, 113 mmol). The mixture was stirred under reflux for 12 hours, and cooled to rt. The precipitate was collected by filtration, and washed with water and ether to give 4-methylphenylmethanesulfonic acid sodium salt (12.5 g, 60 mmol, 53%).

Workup

  1. temperatureunder reflux for 12 hours
  2. filtrationThe precipitate was collected by filtration
  3. washwashed with water and ether

Sources & evidence

ORD record
ord-db9e3cefd35d4332bfd746e68c51ae12
Source dataset
uspto-grants-2001_09
Patent number
US06284768B1

Reaction notes

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