4-Toluenesulfonyl chloride → HCID 15525549, compound

HRID 1594712Notes

Reaction equation

HRID 1594712 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:13][CH2:12][CH2:11][NH:10]2)=[CH:5][CH:4]=1.[C:14]1([CH3:24])[CH:19]=[CH:18][C:17]([S:20](Cl)(=[O:22])=[O:21])=[CH:16][CH:15]=1>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH:9]2[CH2:13][CH2:12][CH2:11][N:10]2[S:20]([C:17]2[CH:18]=[CH:19][C:14]([CH3:24])=[CH:15][CH:16]=2)(=[O:22])=[O:21])=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 37569572-(4-methoxyphenyl)pyrrolidine

Product 1

HCID 15525549HCID 15525549, compound

Procedure

The title compound, white solid, m.p. 122° C. and MS: m/e=332 (M+H+) was prepared in accordance with the general method of example 1e from (RS)-2-(4-methoxy-phenyl)-pyrrolidine and toluene-4-sulfonyl chloride.

Sources & evidence

ORD record
ord-edceb438271d40cfb9632a02c4389431
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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