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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1594714Generated: October 26, 2026

4-Acetylbenzenesulfonyl chloride → (RS)-1-{4-[2-(4-Fluoro-phenyl)-pyrrolidine-1-sulfonyl]-phenyl}-ethanone

https://huagongshe.com/reaction/1594714

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Acetylbenzenesulfonyl chlorideHCID 266418—
Reactant2-(4-Fluorophenyl)pyrrolidineHCID 3865560—
Product(RS)-1-{4-[2-(4-Fluoro-phenyl)-pyrrolidine-1-sulfonyl]-phenyl}-ethanoneHCID 21706702—

Reaction Steps

The title compound, pale brown solid, m.p. 148° C. and MS: m/e=348 (M+H+) was prepared in accordance with the general method of example 1e from (RS)-2-(4-fluoro-phenyl)-pyrrolidine and 4-acetyl-benzenesulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06284785B1
Source datasetuspto-grants-2001_09
ORD IDord-5b7b2ce2200f46388468d7a254bf607e
Source noteuspto-grants-2001_09