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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1594716Generated: October 30, 2026

4-Fluorobenzenesulfonyl chloride → (RS)-1-(4-Fluoro-benzenesulfonyl)-2-m-tolyl-pyrrolidine

https://huagongshe.com/reaction/1594716

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzenesulfonyl chlorideHCID 9588—
Reactant2-(3-Methylphenyl)pyrrolidineHCID 3544098—
Product(RS)-1-(4-Fluoro-benzenesulfonyl)-2-m-tolyl-pyrrolidineHCID 21706703—

Reaction Steps

The title compound, off-white solid, m.p. 80° C. and MS: m/e=319(M+) was prepared in accordance with the general method of example 1e from (RS)-2-m-tolyl-pyrrolidine and 4-fluoro-benzenesulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06284785B1
Source datasetuspto-grants-2001_09
ORD IDord-466ee71548d348d991dbdf758148328d
Source noteuspto-grants-2001_09