4-Toluenesulfonyl chloride → HCID 21706748, compound

HRID 1594717Notes

Reaction equation

HRID 1594717 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]2[CH2:12][CH2:11][CH2:10][NH:9]2)[CH:5]=[CH:6][CH:7]=1.[C:13]1([CH3:23])[CH:18]=[CH:17][C:16]([S:19](Cl)(=[O:21])=[O:20])=[CH:15][CH:14]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]2[CH2:12][CH2:11][CH2:10][N:9]2[S:19]([C:16]2[CH:17]=[CH:18][C:13]([CH3:23])=[CH:14][CH:15]=2)(=[O:21])=[O:20])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 45798062-(3-chlorophenyl)pyrrolidine

Product 1

HCID 21706748HCID 21706748, compound

Procedure

The title compound, off-white solid, m.p. 107° C. and MS: m/e=335 (M+) was prepared in accordance with the general method of example 1e from (RS)-2-(3-chloro-phenyl)-pyrrolidine and toluene-4-sulfonyl chloride.

Sources & evidence

ORD record
ord-96918d2208104b07887a995cfc9dbe40
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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