4-Toluenesulfonyl chloride → HCID 21706712, compound

HRID 1594735Notes

Reaction equation

HRID 1594735 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]1[CH2:12][CH2:11][CH2:10][NH:9]1.[C:13]1([CH3:23])[CH:18]=[CH:17][C:16]([S:19](Cl)(=[O:21])=[O:20])=[CH:15][CH:14]=1>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]1[CH2:12][CH2:11][CH2:10][N:9]1[S:19]([C:16]1[CH:17]=[CH:18][C:13]([CH3:23])=[CH:14][CH:15]=1)(=[O:21])=[O:20]

Participants

3

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 36133062-(2-fluorophenyl)pyrrolidine

Product 1

HCID 21706712HCID 21706712, compound

Procedure

The title compound, white solid, m.p. 143° C. and MS: m/e=320.3 (M+H+) was prepared in accordance with the general method of example 1e from (RS)-2-(2-fluoro-phenyl)-pyrrolidine and toluene-4-sulfonyl chloride.

Sources & evidence

ORD record
ord-1f1cbe4746a842ffbcb70952a1a75415
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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