4-Toluenesulfonyl chloride → HCID 21706759, compound

HRID 1594741Notes

Reaction equation

HRID 1594741 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:12][CH2:11][CH2:10][NH:9]2)=[CH:4][C:3]=1[CH3:13].[C:14]1([CH3:24])[CH:19]=[CH:18][C:17]([S:20](Cl)(=[O:22])=[O:21])=[CH:16][CH:15]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:12][CH2:11][CH2:10][N:9]2[S:20]([C:17]2[CH:18]=[CH:19][C:14]([CH3:24])=[CH:15][CH:16]=2)(=[O:22])=[O:21])=[CH:4][C:3]=1[CH3:13]

Participants

3

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 217067652-(4-Chloro-3-methylphenyl)pyrrolidine

Product 1

HCID 21706759HCID 21706759, compound

Procedure

The title compound, white solid, m.p. 103° C. and MS: m/e=349 (M+) was prepared in accordance with the general method of example 1e from (RS)-2-(4-chloro-3-methyl-phenyl)-pyrrolidine and toluene-4-sulfonyl chloride.

Sources & evidence

ORD record
ord-836393d6711b4c1fac8ad88d06dcc029
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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