4-Toluenesulfonyl chloride → HCID 21706732, compound

HRID 1594750Notes

Reaction equation

HRID 1594750 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[CH:9]1[CH2:13][CH2:12][CH2:11][NH:10]1.[C:14]1([CH3:24])[CH:19]=[CH:18][C:17]([S:20](Cl)(=[O:22])=[O:21])=[CH:16][CH:15]=1>>[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[CH:9]1[CH2:13][CH2:12][CH2:11][N:10]1[S:20]([C:17]1[CH:18]=[CH:19][C:14]([CH3:24])=[CH:15][CH:16]=1)(=[O:22])=[O:21]

Participants

3

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 3990120HCID 3990120, compound

Product 1

HCID 21706732HCID 21706732, compound

Procedure

The title compound, white solid, m.p. 130° C. and MS: m/e=329 (M+) was prepared in accordance with the general method of example 1e from (RS)-2-(2,4-dimethyl-phenyl)-pyrrolidine and toluene-4-sulfonyl chloride.

Sources & evidence

ORD record
ord-2212217a418149d8a8e4cc30956d9bfc
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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