4-Toluenesulfonyl chloride → HCID 21706721, compound

HRID 1594758Notes

Reaction equation

HRID 1594758 reaction equation
[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([CH:9]2[CH2:13][CH2:12][CH2:11][NH:10]2)=[CH:5][CH:4]=1)[CH3:2].[C:14]1([CH3:24])[CH:19]=[CH:18][C:17]([S:20](Cl)(=[O:22])=[O:21])=[CH:16][CH:15]=1>>[CH2:1]([C:3]1[CH:4]=[CH:5][C:6]([CH:9]2[CH2:13][CH2:12][CH2:11][N:10]2[S:20]([C:17]2[CH:18]=[CH:19][C:14]([CH3:24])=[CH:15][CH:16]=2)(=[O:22])=[O:21])=[CH:7][CH:8]=1)[CH3:2]

Participants

3

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 3901423HCID 3901423, compound

Product 1

HCID 21706721HCID 21706721, compound

Procedure

The title compound, white solid, m.p. 92° C. and MS: m/e=330.3 (M+H+) was prepared in accordance with the general method of example 1e from (RS)-2-(4-ethyl-phenyl)-pyrrolidine and toluene-4-sulfonyl chloride.

Sources & evidence

ORD record
ord-faa32f2135164af7982c4dc0ca247d36
Source dataset
uspto-grants-2001_09
Patent number
US06284785B1

Reaction notes

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