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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 159478Generated: October 26, 2026

Hydrochloric Acid → 2'-(1H-Tetrazol-5-yl)-1,1'-biphenyl-4-carboxaldehyde (Losartan Impurity)

https://huagongshe.com/reaction/159478

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDimethyl SulfoxideHCID 679—
ReactantPyridineHCID 1049—
ReactantTriethylamineHCID 8471—
ReactantEthyl AcetateHCID 8857—
ReactantSulfur trioxideHCID 24682—
Reactant(2'-(1H-Tetrazol-5-yl)biphenyl-4-yl)methanolHCID 178519405—
Product2'-(1H-Tetrazol-5-yl)-1,1'-biphenyl-4-carboxaldehyde (Losartan Impurity)HCID 178519404—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-f237702cfee148c6b1687c841fb7c83a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)