Hydrochloric Acid → 2'-(1H-Tetrazol-5-yl)-1,1'-biphenyl-4-carboxaldehyde (Losartan Impurity)
Reaction equation
[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[CH3:38][S:39]([CH3:40])=[O:41].[CH3:42][CH2:43][O:44][C:45](=[O:46])[CH3:47].[ClH:37].[S:33](=[O:34])(=[O:35])=[O:36].[n:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1.[nH:1]1[n:2][n:3][n:4][c:5]1-[c:6]1[c:7](-[c:12]2[cH:13][cH:14][c:15]([CH2:18][OH:19])[cH:16][cH:17]2)[cH:8][cH:9][cH:10][cH:11]1>>[n:1]1[n:2][n:3][nH:4][c:5]1-[c:6]1[c:7](-[c:12]2[cH:13][cH:14][c:15]([CH:18]=[O:19])[cH:16][cH:17]2)[cH:8][cH:9][cH:10][cH:11]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-f237702cfee148c6b1687c841fb7c83a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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