3-Ethylhexahydro-3-(3-hydroxyphenyl)-1-methyl-2H-azepin-2-one → 2-[3-(3-ethyl-1-methyl-2-oxo-azepan-3-yl)-phenoxy]-4-[-(3-methyl-3-H-imidazol-4-yl)-cyclopropyl]-benzonitrile

Participants

Reaction Steps

Using the procedure described in Example 3, the title compound was prepared starting with 2-fluoro-4-[1-(3-methyl-3-H-imidazol-4-yl)-cyclopropyl]-benzonitrile (as described in Step A above) (0.050 g, 0.21 mmol) and 3-ethyl-3-(3-hydroxy-phenyl)-1-methyl-azepan-2-one (0.078 g, 0.21 mmol).

Provenance & Evidence