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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1594898Generated: October 31, 2026

HCID 21706154, compound → HCID 21706292, compound

https://huagongshe.com/reaction/1594898

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21706154HCID 21706154—
CatalystManganese dioxideHCID 14801—
SolventDichloromethaneHCID 6344—
ProductHCID 21706292HCID 21706292—

Reaction Steps

To a solution of 4-[(4-allyl-5-bromo-pyridine-3-yl)-hydroxy-methyl]-2-fluoro-benzonitrile (as described above in Step B) (0.42 g, 1.21 mmol) in CH2Cl2 (50 mL) was added MnO2 (1.58 g, 18.1 mmol). After 6 hr the reaction was filtered and the CH2Cl2 was removed in vacuo to obtain the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06284755B1
Source datasetuspto-grants-2001_09
ORD IDord-d8e9d249c0a04ca8950fe2168433448d
Source noteuspto-grants-2001_09