HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21706154, compound → HCID 21706292, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21706154 | HCID 21706154 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 21706292 | HCID 21706292 | — |
Reaction Steps
To a solution of 4-[(4-allyl-5-bromo-pyridine-3-yl)-hydroxy-methyl]-2-fluoro-benzonitrile (as described above in Step B) (0.42 g, 1.21 mmol) in CH2Cl2 (50 mL) was added MnO2 (1.58 g, 18.1 mmol). After 6 hr the reaction was filtered and the CH2Cl2 was removed in vacuo to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06284755B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-d8e9d249c0a04ca8950fe2168433448d |
| Source note | uspto-grants-2001_09 |