Boron tribromide → HCID 21706220, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 1-(2-dimethylamino-ethyl)-3-ethyl-3-(3-methoxy-phenyl)-azepan-2-one Trifluoroacetate (as described above in Step A) (0.1 g, 0.23 mmol) in CH2Cl2 (10 mL) at −78° C. was added BBr3 (1M, 0.46 mL, 0.46 mmol). After stirring for 2 hr at 25° C. the reaction mixture was quenched with H2O, the solvents removed in vacuo, and the residue purified by prep RP HPLC to obtain the title compound.

Provenance & Evidence