HuagongsheHuagongshe Chemistry Print Report · For research reference only
(+)-4-[1-amino-1-(3-methyl-3H-imidazol-4-yl)-ethyl]-2-fluoro-benzonitrile → 4-[1-amino-1-(3-methyl-3H-imidazol-4-yl)-ethyl]-2-[3-(morpholine-4-sulfonyl)-phenoxy]-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (+)-4-[1-amino-1-(3-methyl-3H-imidazol-4-yl)-ethyl]-2-fluoro-benzonitrile | HCID 11470581 | — |
| Reactant | 3-(Morpholin-4-ylsulfonyl)phenol | HCID 15027330 | — |
| Product | 4-[1-amino-1-(3-methyl-3H-imidazol-4-yl)-ethyl]-2-[3-(morpholine-4-sulfonyl)-phenoxy]-benzonitrile | HCID 21706293 | — |
Reaction Steps
Using the methods described in Example 24A, but substituting 3-hydroxybenzenesulfonylmorpholine (0.015 g, 0.061 mmol) and 2-fluoro-4-[1-amino-1-(3-methyl-3H-imidazol-4-yl)-ethyl]-benzonitrile (as described in Example 24A, Step F), the title compound was prepared.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06284755B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-37ef510d6bd64289812cf94435ffb77a |
| Source note | uspto-grants-2001_09 |