HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)- → 3alpha-N-(N-tert-butyloxycarbonyl-O-benzyl-L-seryl)aminocholestane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)- | HCID 90234 | — |
| Reactant | 3Alpha-aminocholestane | HCID 10872780 | — |
| Product | 3alpha-N-(N-tert-butyloxycarbonyl-O-benzyl-L-seryl)aminocholestane | HCID 54282506 | 90.4% |
Reaction Steps
By using N-tert-butyloxycarbonyl-O-benzyl-L-serine (2.28 g, 7.72 mmol) and 3α-aminocholestane (3.00 g, 7.74 mmol), the title compound was obtained in the same manner as in Synthetic Example BB1 (4.64 g, yield; 90.4%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06288041B1 |
| Source dataset | uspto-grants-2001_09 |
| ORD ID | ord-441f861f4ac24699808eda06372fd685 |
| Source note | uspto-grants-2001_09 |