Cyanamide → HCID 178453081, compound

HRID 1595216Notes

Reaction equation

HRID 1595216 reaction equation
[NH2:1][C:2]1[CH:23]=[CH:22][C:5]([CH2:6][N:7]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])=[CH:4][CH:3]=1.[N:24]#[C:25][NH2:26]>C(O)C>[NH2:26][C:25]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][N:7]([C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[C:8]([O:10][C:11]([CH3:13])([CH3:14])[CH3:12])=[O:9])=[CH:22][CH:23]=1)=[NH:24]

Participants

4

Reactant 2

HCID 9864CyanamideHCID 70235112HCID 70235112, compound

Product 1

HCID 178453081HCID 178453081, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

10 mmol of di-(tert-butyl) 4-aminobenzylimidodicarbonate and 100 mmol of cyanamide are heated at reflux for 2 days in 80 ml of anhydrous ethanol. Removal of the ethanol by evaporation, and purification by chromatography on silica, yield the expected product.

Workup

  1. customRemoval of the ethanol
  2. customby evaporation, and purification by chromatography on silica

Sources & evidence

ORD record
ord-5b049efca06b40b7bb801bb8774b6c85
Source dataset
uspto-grants-2001_09
Patent number
US06288077B1

Reaction notes

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