反应详情

Ethyl 2-hydroxyimino-3-(4-methylphenyl)-3-oxopropionate (10.5 g) and 4-aminomethylpyridine (5.8 g) were dissolved in xylene (100 ml), and the mixture was reacted and treated in the same manner as in Starting Material Synthetic Example 1 to give ethyl 5-(4-methylphenyl)-2-(4-pyridyl)imidazole-4-carboxylate (54.2 g), melting point 182-185° C.

1. customthe mixture was reacted
2. additiontreated in the same manner as