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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1595360Generated: October 26, 2026

3-Nitrobenzylamine → Ethyl 5-(4-methoxyphenyl)-2-(3-nitrophenyl)imidazole-4-carboxylate

https://huagongshe.com/reaction/1595360

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-NitrobenzylamineHCID 122722—
ReactantHCID 178472900HCID 178472900—
ProductEthyl 5-(4-methoxyphenyl)-2-(3-nitrophenyl)imidazole-4-carboxylateHCID 17847018845.5%

Reaction Steps

Ethyl 2-hydroxyimino-3-(4-methoxyphenyl)-3-oxopropionate (20.0 g) and 3-nitrobenzylamine (15.0 g) were reacted and treated in the same manner as in Starting Material Synthetic Example 10 to give ethyl 5-(4-methoxyphenyl)-2-(3-nitrophenyl)imidazole-4-carboxylate (13.3 g), melting point 208-210° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06288061B1
Source datasetuspto-grants-2001_09
ORD IDord-6207b02a828b4dacb96a62bf96f738ab
Source noteuspto-grants-2001_09