HCID 178475833, compound → HCID 178475832, compound

HRID 1595382Notes

Reaction equation

HRID 1595382 reaction equation
[C:1]([O:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[NH:13][C:14]([C:24]3[CH:29]=[CH:28][C:27]([Cl:30])=[CH:26][CH:25]=3)=[C:15]([C:17]([O:19]C(C)(C)C)=[O:18])[N:16]=2)=[CH:8][CH:7]=1)(=[O:3])[CH3:2]>FC(F)(F)C(O)=O>[C:1]([O:4][CH2:5][C:6]1[CH:7]=[CH:8][C:9]([C:12]2[NH:13][C:14]([C:24]3[CH:25]=[CH:26][C:27]([Cl:30])=[CH:28][CH:29]=3)=[C:15]([C:17]([OH:19])=[O:18])[N:16]=2)=[CH:10][CH:11]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 1

HCID 178475833HCID 178475833, compound

Product 1

HCID 178475832HCID 178475832, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

tert-Butyl 2-(4-acetoxymethylphenyl)-5-(4-chlorophenyl)-imidazole-4-carboxylate is dissolved in trifluoroacetic acid, and the solution is stirred at room temperature to give the objective 2-(4-acetoxymethylphenyl)-5-(4-chlorophenyl)imidazole-4-carboxylic acid.

Sources & evidence

ORD record
ord-014742548a934c6b923375713d32b8a3
Source dataset
uspto-grants-2001_09
Patent number
US06288061B1

Reaction notes

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