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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1595384Generated: November 2, 2026

HCID 21703930, compound → HCID 178450800, compound

https://huagongshe.com/reaction/1595384

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21703930HCID 21703930—
ReactantHCID 178451307HCID 178451307—
SolventPyridineHCID 1049—
ProductHCID 178450800HCID 178450800—

Reaction Steps

4-[4-(2-Hydroxyethyl)piperazin-1-yl]phenylmethylamine and tert-butyl 3-(4-chlorophenyl)-2-hydroxyimino-3-oxopropionate are dissolved in pyridine, and the solution is treated in the same manner as in Starting Material Synthetic Example 170 to give the objective tert-butyl 5-(4-chlorophenyl)-2-{4-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl}imidazole-4-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06288061B1
Source datasetuspto-grants-2001_09
ORD IDord-9557475b081546a08b78299102745fc7
Source noteuspto-grants-2001_09