Stannous Chloride → HCID 178507450, compound

HRID 1595395Notes

Reaction equation

HRID 1595395 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[NH:11][C:12]([C:23]3[CH:28]=[CH:27][C:26]([N+:29]([O-])=O)=[CH:25][CH:24]=3)=[C:13]([C:15]([NH:17][C:18]3[S:19][CH:20]=[CH:21][N:22]=3)=[O:16])[N:14]=2)=[CH:6][CH:5]=1)([O-])=O.[Sn](Cl)Cl>CO.Cl>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[NH:11][C:12]([C:23]3[CH:28]=[CH:27][C:26]([NH2:29])=[CH:25][CH:24]=3)=[C:13]([C:15]([NH:17][C:18]3[S:19][CH:20]=[CH:21][N:22]=3)=[O:16])[N:14]=2)=[CH:8][CH:9]=1

Participants

5

Reactant 2

HCID 24479Stannous ChlorideHCID 178522575HCID 178522575, compound

Product 1

HCID 178507450HCID 178507450, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 887MethanolSolvent

Procedure

2,5-bis(4-Nitrophenyl)-N-(2-thiazolyl)imidazole-4-carboxamide obtained in Example 53 is suspended in methanol and ice-cooled. To the suspension is added a solution of tin(II) chloride 6 hydrate in 6 M hydrochloric acid solution and the mixture is reacted and treated in the same manner as in Example 48 to give 2,5-bis(4-aminophenyl)-N-(2-thiazolyl)imidazole-4-carboxamide.

Workup

  1. temperatureice-cooled
  2. customthe mixture is reacted
  3. additiontreated in the same manner as in Example 48

Sources & evidence

ORD record
ord-2e0af8351c254a98b25d3290e49ad7ec
Source dataset
uspto-grants-2001_09
Patent number
US06288061B1

Reaction notes

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